Controlled vocabularies and semantics in systems biology
نویسندگان
چکیده
منابع مشابه
Controlled vocabularies and semantics in systems biology
The use of computational modeling to describe and analyze biological systems is at the heart of systems biology. Model structures, simulation descriptions and numerical results can be encoded in structured formats, but there is an increasing need to provide an additional semantic layer. Semantic information adds meaning to components of structured descriptions to help identify and interpret the...
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A major problem that arises in many large application domains is the discrepancy among terminologies of diierent information systems. The terms used by the information systems of one organization may not agree with the terms used by another organization even when they are in the same domain. Such a situation clearly impedes communication and the sharing of information, and decreases the eecienc...
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A vocabulary stores words, synonyms, word sense definitions (i.e. glosses), relations between word senses and concepts; such a vocabulary is generally referred to as the Controlled Vocabulary if choice or selections of terms are done by domain specialists. In our case,we create and match two controlled vocabularies by using their concept facet. This methodology is based on semantic matching whi...
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For the foreseeable future, controlled medical vocabularies will be in a constant state of development, expansion and refinement. Changes in controlled vocabularies must be reconciled with historical patient information which is coded using those vocabularies and stored in clinical databases. This paper explores the kinds of changes that can occur in controlled vocabularies, including adding te...
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ژورنال
عنوان ژورنال: Molecular Systems Biology
سال: 2011
ISSN: 1744-4292,1744-4292
DOI: 10.1038/msb.2011.77